Description
Dosage
Composition
Literature
FAQ
Reviews
A veterinary supplement for small breed dogs with joint issues and young dogs in a rapid growth phase with cartilage development problems.
The HA Mini tablet is specially designed to be small and easy to give to small breed dogs.
Hydrolyzed collagen (<2500 Daltons) – nourishes and supports the regeneration of joints and other connective tissues in the body. It provides free amino acids, peptides and collagen fibers, necessary for the synthesis of collagen in the body [1]. Due to its low molecular weight, it has higher absorption and better bioactive properties [2]. Regularly supplemented, it improves the mobility and flexibility of joints, and visibly reduces pain in the course of degenerative joint and spine disease [3,4,5].
Hyaluronic acid – ensures proper viscosity and elasticity of the synovial fluid in the joint capsule, thus increasing joint flexibility and improving mobility [6,7,8].
MSM – supports the proper functioning of joints, accelerates regeneration, has anti-inflammatory effects and relieves pain [9].
Glucosamine – takes an active part in the synthesis of glycosaminoglycans (GAG) [10]. It promotes cartilage regeneration and proper joint functioning. It increases the amount of synovial fluid in the joint capsule, which significantly reduces pain and facilitates movement [10,11,12,13].
Chondroitin – improves the elasticity of cartilage tissues and reduces painful joint swelling [11, 14]. Stimulates the biosynthesis of hyaluronic acid and proteoglycans, which give cartilage elasticity and resistance to deformation [15].
Vitamin C – stimulates the synthesis of proteoglycans, is necessary for the formation and secretion of ossein (a building block of bones). It enhances the processes of collagen synthesis and prevents its degeneration in the body [16].
AniFlexi HA Mini: 120 tablets
Joint dysplasia
Degeneration of joints and spine
Inflammation in the joints
Dosage
AniFlexi HA Mini
| 3 kg | 1 tablet | |
| 6 kg | 2 tablets | |
| 9 kg | 3 tablets |
Active substances
in 1 tablet
Hydrolyzed collagen
110 mg
Hyaluronic acid
12,5 mg
Glucosamine sulfate
35 mg
Chondroitin sulfate
12,5 mg
MSM
10 mg
Vitamin C
7,5 mg
Composition
Hydrolyzed collagen (bovine) 40%, glucosamine (from marine crustaceans) 13%, chondroitin sulfate (bovine) 5%, sodium hyaluronate 5%, MSM 4%, Additives : Vitamine C Technological additives: microcrytsalline cellulose, magnesium stearate
Analytical constituents
- protein 46%
- crude oils and fats 0,1%
- crude ash 6%
- crude fibre 21%
1. Tang C., Zhou K., Zhu Y., Zhang W., Xie Y., Wang Z., Zhou H., Yang T., Zhang Q., Xu B. Collagen and Its Derivatives: From Structure and Properties to Their Applications in Food Industry. Food Hydrocoll. 2022, 131, 107748.
2. Hong H., Fan H., Chalamaiah M., Wu J. Preparation of Low-Molecular-Weight, Collagen Hydrolysates (Peptides): Current Progress, Challenges, and Future Perspectives. Food Chem. 2019, 301, 125222.
3. Weide N. Der Einsatz von Gelatinehydrolysat bei klinisch-orthopädisch gesunden Hunden und Hunden mit chronischen Erkrankungen des Bewegungsapparats. PhD thesis. Tierärztliche Hochschule Hannover, 2004.
4. Hesse, K.J.F. Supplementation by Collagen Hydrolysate in Dogs Suffering from Osteoarthritis. Kleintiermedizin.2006, 9, 17-22.
5. Bello AE, Oesser S. Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature. Curr Med Res Opin. 2006 Nov;22(11):2221-32.
6. Evanko S.P., Tammi M.I., Tammi R.H., Wight T.N. Hyaluronan-dependent pericellular matrix. Adv. Drug Deliv. Rev. 2007, 59, 1351–1365.
7. Plickert H., Bondzio A., Einspanier R., Tichy A., Brunnberg, L. Hyaluronic acid concentrations in synovial fluid of dogs with different stages of osteoarthritis. Res. Veter. Sci. 2013, 94, 728–734.
8. Serra Aguado C.I., Ramos-Plá J.J., Soler C., Segarra S., Moratalla V., Redondo J.I. Effects of Oral Hyaluronic Acid Administration in Dogs Following Tibial Tuberosity Advancement Surgery for Cranial Cruciate Ligament Injury. Animals (Basel). 2021 Apr 27;11(5):1264.
9. Pagonis, Thomas & Givissis, Panagiotis & Kritis, Aristeidis & Christodoulou, Anastasios. (2014). The Effect of Methylsulfonylmethane on Osteoarthritic Large Joints and Mobility. International Journal of Orthopaedics. 1. 1-6.
10. Henrotin Y., Mobasheri A., Marty M. Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis? Arthritis Res Ther. 2012;14(1):201.
11. Jerosch J. Effects of glucosamine and chondroitin sulfate on cartilage metabolism in OA: outlook on other nutrient partners especially omega-3 fatty acids. Int. J. Rheumatol. 2011;2011:969012.
12. Dodge G.R., Regatte R.R., Noyszewski E.A., Hall J.O., Sharma A.V., Callaway D.A., Reddy R. The Fate of Oral Glucosamine Traced by (13)C Labeling in the Dog. Cartilage. 2011 Jul;2(3):279-85.
13. Wenz W., Hornung C., Cramer C., Schroeder M., Hoffmann M. Effect of Glucosamine Sulfate on Osteoarthritis in the Cruciate-Deficient Canine Model of Osteoarthritis. Cartilage. 2017 Apr;8(2):173-179.
14. McCarthy G., O’Donovan J., Jones B., McAllister H., Seed M., Mooney C. Randomised double-blind, positive-controlled trial to assess the efficacy of glucosamine/chondroitin sulfate for the treatment of dogs with osteoarthritis. Vet J. 2007;174(1):54-61.
15. Iovu M., Dumais G., duSouich P. Anti-inflammatory activity of chondroitin sulfate. Osteoarthritis Cartilage 2008;16(suppl 3):S14–S18
16. Ripani U, Manzarbeitia-Arroba P, Guijarro-Leo S, Urrutia-Graña J, De Masi-De Luca A. Vitamin C May Help to Reduce the Knee’s Arthritic Symptoms. Outcomes Assessment of Nutriceutical Therapy. Med Arch. 2019 Jun;73(3):173-177.
Is this product suitable for puppies?
The product is safe for puppies and is an excellent choice for disorders of the motor system development in growing dogs. However, if the puppy is healthy and does not show any problems with the motor system, then we definitely recommend AniFlexi Fit – a product dedicated to supporting the development of the motor system of puppies.
Will this product help with tracheal collapse?
Yes, this is a product that is worth using in case of tracheal collapse, due to the content of substances that strengthen the cartilage.
Should I take breaks from use?
We do not recommend taking breaks in using this product.
5 reviews for Game Dog AniFlexi HA Mini
Only logged in customers who have purchased this product may leave a review.
pati.kepa –
Stosujemy u naszej suczki Nuki, która ma 10 lat. Zaczęły się problemy z chodzeniem, poruszaniem, ale dzięki temu produktowi nastąpiła znaczna poprawa. Szczerze polecam !
na-pomoc-ast1 –
Od ponad miesiąca stosuje u swojego kundelka staruszka. Widać znaczna poprawę, chód pieska jest pewniejszy. Polecam bardzo serdecznie!
na-pomoc-ast –
Od ponad miesiąca stosuje u swojego kundelka staruszka. Widać znaczna poprawę, chód pieska jest pewniejszy. Polecam bardzo serdecznie!
Wioetta –
Polecam ,produkt i wspaniałym działaniu . Podaję szpicom miniaturowym w ròżnym wieku .Powròciła witalność, lepsza kondycja, bardzo wspomógł pieska ,przy zapadającej się tchawicy, objawy u jednego bardzo złagodniały u drugiego zniknęły zupełnie.
Game dog aniflax –
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